Recently, a collaborative research team hailing from the United States and Japan has successfully developed the most extensive and intricately detailed animal brain simulation system ever created, leveraging Japan's state-of-the-art supercomputer, Fugaku. Drawing inspiration from the mouse cerebral cortex, this groundbreaking system encompasses nearly 10 million neurons, a staggering 26 billion synapses, and 86 distinct brain regions, achieving an unprecedented degree of structural and functional accuracy. Armed with this model, scientists are now equipped to simulate the progression of neurological conditions such as Alzheimer's disease and epilepsy, delve into the intricacies of brain wave formation, explore the neural underpinnings of attention, and trace the propagation pathways of epileptic seizures. This breakthrough substantially boosts research efficiency and lays a solid foundation for uncovering early alterations in brain diseases and fostering the development of novel drugs.