The biomanufacturing team within the Department of Mechanical Engineering at Tsinghua University has recently pioneered a groundbreaking DNA storage system based on the Primer Disk. This system capitalizes on the inherent advantages of DNA, including its high density, longevity, low energy consumption, and robust security, to offer append-write, indexing, and multiple read (RMRM) capabilities. This innovative approach provides a novel solution for large-scale DNA data archiving. In contrast to traditional DNA storage methods, which are constrained by the need to store indexing information on separate media and the inability to perform continuous data operations, the Tsinghua team has triumphantly addressed these limitations. Through the covalent attachment of oligonucleotide chains to disks, combined with advanced inkjet printing and enzyme processing technologies, the team has not only enhanced the operability of the DNA storage system but also facilitated information indexing and multiple random reads via fluorescent dot matrix and solid-phase PCR technologies. The team has verified the system's data fidelity after numerous append-writes and reads, and their research findings have been featured in the esteemed journal Advanced Science.