The three major A-share indices commenced trading on a downbeat note. The Shanghai Composite Index kicked off the session 0.35% in the red, while the Shenzhen Component Index followed suit, opening 0.38% lower. The ChiNext Index wasn't spared either, starting the day 0.42% down. In contrast, the newly listed stock N Haochuangruitong witnessed a meteoric rise, soaring by more than 176%. Among the sectors that faced significant headwinds, the biotechnology, pharmaceutical, and semiconductor industries stood out as the top losers. Cayman Pharmaceuticals took a substantial hit, plummeting by over 3%. Meanwhile, Joinn Laboratories, Pharmaron, and VeriSilicon also saw their share prices drop by more than 2%. On the flip side, certain sectors managed to buck the trend and post gains. The beverage, energy equipment, and automotive sectors emerged as the frontrunners. Yangyuan Beverage hit the daily limit, indicating strong buying interest. China Petroleum Engineering surged by over 5%, and Seres climbed by more than 2%, showcasing resilience in these sectors amidst the overall market downturn.