Recently, a collaborative effort between the research team led by Zang Faheng from the School of Integrated Circuits at Shanghai Jiao Tong University and the team led by Xu Yi from the College of Plant Protection at Nanjing Agricultural University has yielded a significant advancement. They have successfully developed an ultra-sensitive porous nano-optical antenna array biosensing chip, tailored specifically for the detection of the Soybean Stunt Glycine Virus (SoSGV).
Leveraging cutting-edge three-dimensional nanoscale fabrication techniques, this innovative chip seamlessly integrates macroscopic array architectures with nanoscale metal apertures. This integration substantially boosts the sensitivity of biomolecule detection, setting a new benchmark in the field.
Experimental data reveal a remarkable enhancement: when detecting the Soybean Stunt Glycine Virus, the fluorescence signal intensity generated by the chip soared over 500 times compared to that of a conventional gold substrate. This striking increase underscores the chip's potential as a groundbreaking, cost-effective, and highly sensitive platform for biosensing applications.
The research findings associated with this breakthrough have been published in the esteemed journal Advanced Optical Materials, marking a significant contribution to the scientific community.