Gu Quanquan, a pivotal figure in ByteDance's Seed team with a specialization in AI for Science (AI4S), has officially departed from the company. Throughout his tenure at ByteDance, he played a leading role in spearheading AI-driven initiatives for drug discovery, developing innovative models including SeedFold, SeedProteo, and the DPLM series. Subsequently, he transitioned to the LLM pre-training team, where he established the LLM optimization and scaling team, providing crucial support for the training of Seed 2.0 and its successor models. Prior to his departure, whispers of organizational reshuffles within ByteDance's AI4S team had been circulating, with conjecture mounting that several key members might depart to launch their own startups. In response, ByteDance clarified that the team is now under the capable leadership of Yang Zhenyuan, with no intentions of undergoing a split. As for Gu Quanquan's future endeavors, he has remained tight-lipped, but rumors abound that he may delve into the realms of AI-driven pharmaceuticals, protein design, and drug discovery platforms.