CSPC Pharmaceutical Group and Madrigal Pharmaceuticals have inked a groundbreaking deal, whereby Madrigal will secure the worldwide exclusive license to develop, manufacture, and market SYH2086, an orally administered GLP-1 small molecule agonist independently crafted by CSPC. This agreement involves an upfront payment of USD 120 million, with potential milestone payments reaching up to USD 1.955 billion, totaling a maximum consideration of USD 2.075 billion. Notably, CSPC Pharmaceutical Group retains the exclusive rights to develop and commercialize additional orally administered GLP-1 small molecule products within the Chinese market.