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For the first time, a research team from Oregon Health & Science University in the United States has harnessed the power of cryogenic electron microscopy to unveil the intricate structures of key neural receptors located in the cerebrum and cerebellum. Their groundbreaking findings, published in the esteemed journal Nature, delve into the glutamate receptor and its associated protein complex within the cerebellum, elucidating their structures with near-atomic precision. This revelation serves as a cornerstone for comprehending the underlying mechanisms of motor control, learning, and memory. Furthermore, it holds promise for advancing the repair of impaired synaptic connections, potentially opening new avenues for the treatment of neurodegenerative diseases and movement disorders.
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