On the 100th anniversary of the inception of quantum mechanics, the Royal Swedish Academy of Sciences made a historic announcement on October 7. It declared that the 2025 Nobel Prize in Physics would be bestowed upon three distinguished quantum physicists: John Clarke, Michel H. Devoret, and John M. Martinis. This prestigious award was given in recognition of their remarkable contributions to realizing macroscopic quantum mechanical tunneling effects as well as energy quantization within circuits. Their groundbreaking work has opened up the possibility of observing quantum phenomena at a macroscopic level. Moreover, it has laid a solid foundation for the advancement of next-generation quantum technologies, including but not limited to quantum cryptography, quantum computers, and quantum sensors.